Thursday, October 6, 2011

Blood Sugar Negative Feedback Loop


Human bodies tend to prefer to stay in a steady state or homeostasis with almost every substance in their body. Blood sugar or glucose is no exception to this. A person's blood sugar will raise and lower periodically based on their activity. Suppose someone were to eat a sugary candy bar and drink a sugar rich drink such as Mtn. Dew. This would cause a major spike in their blood sugar level. The body has a physiological mechanism that helps it to reduce this spike in blood sugar and reach that steady state again. When there is a high level of glucose in the blood the pancreas trigger their Beta cells to produce the hormone insulin. This hormone helps to convert glucose into a form that it can be stored in the body known as glycogen. Insulin also stimulates about 2/3 of body cells such as muscle and fat tissue cells to absorb glucose These two processes of body cells absorbing glucose and converting glucose to glycogen for storage help to lower the level of glucose in the blood. This will continue until blood sugar levels reach the steady state or homeostasis again. This is an example of a negative feedback loop in the body. The graph above gives a graphical representation of the spike in blood sugar and then the decent back to the bodies' steady state.

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